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diagnosis hepatology differential management algorithm injury lfts syndrome transaminitis ascites hbv hepatitisb hepatopulmonary rheumatology aclf aih arthritis autoimmune cellulitis chemistry
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... #Chronic #Liver ... #Failure #Cirrhosis
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Nonalcoholic fatty liver ... heart failure (chronic ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... • Chronic Viral ... Hepatitis Moderate ... Hepatopathy • Acute ... Viral Hepatitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Injury #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Portal Hypertension ... /acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... viremia or have cirrhosis ... Chronic Hepatitis ... Diagnosis #Management #Treatment ... #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... Infiltrative disease • Acute ... liver failure ... #causes
Causes of Gallbladder Wall Thickening - Differential Diagnosis • Physiologic: Contracted gall bladder in a non-fasting
Causes of Gallbladder ... heart failure, Liver ... cirrhosis, Nephrotic ... & chronic cholecystitis ... hepatitis, Pancreatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... or chronic atypical ... hepatitis fibrosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
cirrhosis, chronic ... cirrhosis, chronic ... Kidney stones caused ... cirrhosis, chronic ... Tolvaptan) • Treatment
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