32 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... 30%) • Facial Nerve ... • Pain: Due to nerve ... #diagnosis #management
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Diagnostic Criteria for Guillain ... Features Required for Guillain-Barré ... , Mild sensory symptoms ... signs, Cranial nerve ... BrighamMedRes #Guillain
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... #Barre #Syndrome ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... Diagnosis and Management ... factors affecting symptom ... #Pathophysiology ... #Diagnosis #Management
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... damage to sacral nerves ... #MSK #pathophysiology ... #diagnosis #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
small joints (wrists ... Stimulation of nerve ... fingers, radial wrist ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... compression of nerve ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Tethered cord • Guillain-Barre
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
hypothyroid-induced myopathy, Guillain-Barré ... syndrome (GBS), ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome ... myopathy #diagnosis #management