4 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... e.g. lupus, CLL, lymphoma ... #Causes #differential ... #diagnosis #hematology ... #anemia
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... Immunohistochemical studies (to differentiate
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... disorder or lymphoid ... - Monoclonal - Lymphoid ... CLL (older) • Autoimmune ... younger pts) Differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... Cirrhosis, ETOH, autoimmune ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential