32 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... #Disease #differential ... #diagnosis #causes ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Bone and joint ... anterior chest wall, parts ... Rule out other causes ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... candidate) - Bone ... #Causes #Workup ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... Like in this case ... #rheumatology # ... approach #workup
Hand X-Ray Anatomy and Interpretation Checklist
1. Soft tissues - Look carefully at the soft tissue over
into the hand and wrist ... In case of a fracture ... important to look for signs ... rheumatological diseases ... Interpretation #Checklist #radiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
distal to elbows/wrists ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Common Forms of Arthritis in the Hands

Acute Rheumatoid Arthritis 
Tender, painful, stiff joints in rheumatoid arthritis,
metacarpophalangeal, and wrist ... in acute disease ... from bony overgrowth ... #Hands #Types #Rheumatology ... #Forms #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... /joints via hematogenous ... tissue damage - CXR
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... the subchondral bone ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
- Cr >2 mg/dL or ... g/dl LLN B - Bony ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology