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diagnosis hematology mds myelodysplastic sweet anemia aplastic apml classification criteria dermatosis differentiation dress emergencies febrile hodgkins leukostasis lymphoma lysis myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute ... #treatment #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
(Acute Febrile ... inflammatory disease, or pregnancy ... Excellent response to treatment ... rate >20 mm/h; positive ... #Dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Exposure to heavy metal ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
• Syndrome caused ... days after an acute ... including DM • Treatment ... covering both gram positive ... #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... • SJS/TEN • Acute ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Causes: - Idiopathic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
characteristically CD30 positive ... and usually CD15 positive ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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