7 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... : • Defect in fetal ... infiltration) Differential ... Diagnosis: Viral ... iMedEducation #AFLP
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... (AFLP) • Onset ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum ... liver #chemistry #diagnosis ... #differential # ... transaminitis #LFTs
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... metastasis • Fatty ... liver of pregnancy
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... non-alcoholic fatty ... liver disease; ... #LFTs #Abnormal ... Liver #Enzymes #Differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Diagnosis Approach ... previously stable values ... 109 mm Hg) with clinical ... Renal parenchymal disease ... Pregnancy-associated