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diagnosis algorithm liver lfts abnormal hepatitis obstetrics transaminitis alkaline causes chemistry cholangitis cirrhosis comparison disease enzymes fatty hellp icp injury
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... or AST > ALP): ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... - CBD stone, Biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ) Elevation - Differential ... Diagnosis Algorithm ALP ... - Increased ALP ... #Elevation #Differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... specificity to elevated ... ALP • AST/ALT ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
melanoma, myeloma • Pregnancy ... specificity to elevated ... > ALP: Typical ... disease - If ALP ... diagnosis #algorithm #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... (AFLP) • Onset ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
(AFLP) Pathophysiology ... : • Defect in fetal ... infiltration) Differential ... iMedEducation #AFLP ... #hepatology #obstetrics
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
normal or slightly elevated ... obstruction • ALP ... bile ducts Differential ... cholestasis of pregnancy ... diagnosis #workup #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
magnitude of enzyme elevation ... include extrahepatic biliary ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
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