12 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... #Hemolysis #Differential ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Corticosteroid use • Autoimmune ... appreciate the value ... bacteremia and hypotension ... #CBC #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... vasculitis, malignant hypertension ... elliptocytosis, autoimmune ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... : • Defect in fetal ... infiltration) Differential ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... >1.5, and both values ... gastrointestinal bleed, hypotension ... Hepatitis #Diagnosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... melanoma, myeloma • Pregnancy ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Portal Hypertension ... - Differential ... >10 mmHg - clinically ... Fatty liver of pregnancy ... Diagnosis #causes #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... Blood smear - RBC ... younger pts) Differential ... hemolytic #anemia #hematology