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C. Difficile Infection in IBD - IBD Algorithm

Background
Complications
CDI Testing Algorithm
CDI Recurrence

Dr. Wade Billings @wabillin

#Clostridioides #difficile #CDiff
Difficile Infection ... Clostridioides #difficile ... #CDiff #CDifficile ... #Management #Treatment ... #Gastroenterology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection ... Diagnosis and Management ... ciab549 #CDI #Cdiff ... Clostridioides #Difficile ... infectiousdiseases #IDSA #gastroenterology
IBD Mimics
Infectious - Always RULE OUT infection (CMV, C. diff esp.) obtain travel & exposures history:
IBD Mimics Infectious ... infection (CMV, C. diff ... Salmonella • Colon: C. difficile ... lymphomas, others) #IBD ... differential #diagnosis #gastroenterology
Difficult Selective Biliary Cannulation (SBC)
Factors associated with difficult SBC:
 - SMALL PAPILLA: can be difficult to
insertion into the BD ... tract of the MPD & CBD ... ST upward (the BD ... #ercp #gastroenterology ... #management #diagnosis
Constipation Management Algorithm
What do you mean by constipation?
 - Infrequent bowel movements, difficult defecation or both?
Constipation Management ... bowel movements, difficult ... defecation suggests IBS-C ... #Constipation #Management ... #Algorithm #gastroenterology
A proposed management algorithm for CDI in patients with inflammatory bowel disease. *Severe-complicated CDI is defined
A proposed management ... #CDI #CDiff #clostridiumdifficile ... #IBD #Algorithm ... #Gastroenterology ... #Management
Potential Treatment Agents for Treatment of the Primary Clostridium difficile infection Episode
Proven efficacy:
 • Vancomycin -
Primary Clostridium difficile ... Fidaxomicin - 200 mg PO bid ... 50 mg IV every bid ... × 10 days #CDiff ... options #treatment #management
IDSA Recommendations for Preventing and Managing Cryptosporidiosis in HIV-AIDS
Preventing Chronic Cryptosporidiosis:
 • Because chronic cryptosporidiosis occurs
immunosuppressed should ... disease Preferred Management ... Alternative Management ... 500–1000 mg PO BID ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
CMV retinitis should ... feasible, treatment should ... Valganciclovir 900 mg PO BID ... Prevention #Treatment #management ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
Clarithromycin 500 mg PO BID ... Note: Active TB should ... Prevention #Treatment #management ... opportunistic #infections #HIVAIDS