13 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
the knees and hips ... Passive neck flexion causes ... While the pathophysiology ... flexion occurs as ... In very young (less
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... Campylobacter jejuni - HIV ... complete paralysis of all ... Electrodiagnostic studies - EMG
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
risk factors (eg ... hypertension (eg ... hypertension (eg ... Vasculitis • Endocrinologic ... , and Guillain-Barre
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... of UMN and LMN signs ... Escorial criteria uses ... EMG: LMN Signs in
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... Inability to produce all ... humoral immunity Signs ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
exposed tothe sun (e.g ... , oral cavity) Caused ... gluconeogenesis enzymes (e.g ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... symptoms are not caused ... mediators such as ... of diagnosis (e.g ... Diagnosis #Management #Signs
Emergent Causes of Headache and Associated Risk Factors
Carbon monoxide poisoning
 - Breathing in enclosed or confined
Emergent Causes ... carbon monoxide (eg ... living conditions (eg ... vascular diseases (eg ... of the body - Young