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diagnosis differential management algorithm chronic classification elevation fatigue induced lactate lactic lung neurology prs renal rheumatology sjogrens syndromes toxicity toxicology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Chronic Obstructive Pulmonary ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
treatment) • Can ... Acute toxicity (e.g ... respiratory distress syndrome ... Chronic toxicity (e.g ... macrophages Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... before beginning treatment ... output - Acute pulmonary ... - Compartment syndrome
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... mononeuritis multiplex WORKUP ... recent DAN) • EMG ... Goodpasture's cause ... diagnosis #management #treatment
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... Steroids, Statins, amiodarone ... parainfluenza, Coxsackie, HIV ... dystrophies Work ... electromyographic (EMG
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... renal tubular acidosis ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
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