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diagnosis management oncology syndrome lymphoma workup activation antinxp2 antinxp2dm arthritis bleeding cell classification comparison dermatomyositis differential disease disorders erythematosus essential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... underarms, or chest ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Lymphoma - Clinical ... Serum Copper • Chest ... cycles without XR ... classification #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... have fever - ACS ... acid, Elevated Cr ... unless worrisome EKG ... diagnosis #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... • Malignancy (e.g ... Endocrine disorders (e.g ... cyclophosphamide) • Hodgkin ... Erythematosus #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... level, CXR, ANCA ... inflammatory disease (e.g ... Chemistry profile (e.g ... diagnosis #testing #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... involve anterior chest ... antiinflammatory properties e.g ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
indicated • EKG ... Obtain EKG if: ... Change in clinical ... one post op Cardiology ... unless prior heart/lung
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... relatives (if all ... Drug history, e.g ... connective tissue, e.g ... pediatrics #diagnosis #hematology
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