19 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... box indicates all ... Areas of diagnostic ... Abnormal #Algorithm #Hepatology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... #Management #dermatology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... Conditioning regimen Signs ... , unexplained hematologic ... EBV viral load, signs ... #management #transplant
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... , signs, and complications ... transformation into AML ... #Management #Summary ... #treatment #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... approach for post-test ... : Confirmatory test ... D/c all heparin ... #Hematology #HemeOnc
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of all ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... is a skin prick test ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology