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management differential nephrology hyperkalemia hematology classification oncology acidosis algorithm induced syndrome 2016 aace achalasia anemia aniongap antipseudomonal antipseudomonas aplastic colistin
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... • NSAIDs • ACE ... Beta blockers • Antibiotics ... Medications 2. ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... • NSAIDs • ACE ... Beta blockers • Antibiotics ... Medications 2. ... #causes #potassium
AACE/ACE 2016 Postmenopausal Osteoporosis Treatment Algorithm Evaluate for causes of secondary osteoporosis Correct calcium/vitamin D deficiency and address
AACE/ACE 2016 Postmenopausal ... Osteoporosis Treatment ... Evaluate for causes ... • Recommend pharmacologic ... benefits and risks of medications
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Causes of High-anion ... of High-anion Gap ... Potassium-sparing ... ACE-Is and ARBs ... #differential #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... NSAIDs, β-blockers, Antibiotics ... only if no clear cause ... STOP offending medications ... #potassium #nephrology
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease Active Helicobacter pylori—associated ulcer 1. Treat with anti—H pylori
bismuth subcitrate potassium ... completion of antibiotic ... Consider other causes ... #Management #Pharmacology ... #Medications
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... have fever - ACS ... Spontaneous if high ... Syndrome #TLS #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Syndrome (PRES) Overview ... circulation: MCA ACA ... Electrolyte abnormality, Medication ... the underlying cause ... • Treatment of
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... perfusion - shock->treatments ... before beginning treatment ... - HIV/HAART medications ... lactate and can act
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