14 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... Bone/joint pain Psychiatric ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Nigricans • Impaired ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
consequences • Impaired ... AlcoholUseDisorder #EtOH #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Psychiatry
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... chromosome -> Impaired ... Inability to produce all ... humoral immunity Signs ... Agammaglobulinemia #XLinked #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... metabolism which impairs ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of all ... ocular muscles -> Impaired ... Orbital #Cellulitis #pathophysiology ... ophthalmology #diagnosis #signs