13 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... of Sickle Cell Crises ... #Hematology #SickleCell ... Manifestations #Workup #Algorithm ... #Ddxof
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Heart failure - CAD ... of Dyspnea: • Airways ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... TNF blockers had ... #Rheumatology # ... diagnosis #management ... #Dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... hyperviscosity syndrome ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... retinopathy Lab ... differential #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... that are caused ... Out Secondary Causes ... compounds, alcohol, lead ... #diagnosis #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Rheumatology # ... Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... infections with skin ... Transfusion #diagnosis #management ... #hematology #reactions