15 results
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
Base and Blood Gas ... Acidosis - non anion ... gap metabolic acidosis ... - anion gap metabolic ... nickmmark #acidbase #workup
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
Normal Anion-Gap ... Framework and Workup ... VBG - Calculate Anion ... NonAnionGap #Acidosis #Metabolic ... Differential #Diagnosis #Workup
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Start with the Anion ... Diagnosis: • Anion ... Gap Metabolic Acidosis ... Gap Metabolic Acidosis ... Disorders #Evaluation #workup
Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?
Blood Gas (ABG) ... primary problem – metabolic ... or concomitant metabolic ... need to do more work ... = ANION GAP -
Asterixis due to Uremia on Physical Exam

29 year old male came in due to decreasing sensorium
Labs showed high anion ... gap metabolic acidosis ... PhysicalExam #nephrology #clinical
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
of organizing pneumonia ... - Clinical manifestations ... other processes Workup ... strep, HIV • CTD workup ... COP DDX: • CAP
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... the osmolal and anion ... Conversely, the serum anion ... onset of the high anion-gap ... #Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... Due to neuronal metabolism ... 3) Follow the anion ... gap until it closes ... DiabeticKetoacidosis #DKA #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... , ↑Tbili/Dbili/AP ... Maternal Support - Critical
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Diagnosis and Workup ... Endocrinology #Treatment #Pathophysiology