antidote pharmacology anterior dosing anticoagulation oral dabigatran anticoagulant cascade clot

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Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster

#VTE #DOAC #Bridging #Dosing #Oral

Oral anticoagulant ... #Oral #Anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology

The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.

During the initiation ... platelet #thrombin #clot ... pathophysiology #anticoagulation ... #anticoagulant ... #Warfarin #Dabigatran

Perioperative Management of DOACs
Problem:
✖ Each year approximately 250,000 patients on chronic anticoagulation in North America

direct acting oral ... anticoagulants ... clearance (calculated using ... of Therapy • Dabigatran ... Management #Treatment #pharmacology

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