349 results
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
clotting #INR #heparin ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Anticoagulants • Heparin ... Unfractionated heparin ... : Rivaroxaban, Apixaban ... Inhibitors: Argatroban, Dabigatran
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Warfarin - 100% Hepatic ... , 0% Renal Apixaban ... - 75% Hepatic, ... 25% Renal Dabigatran ... - 20% Hepatic,
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) - Heparin ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... Xa inhibitors - Apixaban ... ) inhibitors - Dabigatran
Very Quick Guide to Reversing Antithrombotic Therapy
Aspirin 
Clopidogrel 
Prasugrel 
Ticagrelor 
Abciximab 
Tirofiban 
Eptifibatide 
Unfractionated Heparin 
Low
Unfractionated Heparin ... Molecular Weight Heparin ... Bivalirudin Dabigatran ... Apixaban Betrixaban
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy
Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Unfractionated Heparin ... Molecular Weight Heparin ... , Bivalirudin, Dabigatran ... , Apixaban, Betrixaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... Unfractionated heparin ... smaller average heparin ... LMWH #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
anticoagulant #Warfarin #Dabigatran ... thrombin #inhibitor #Apixaban ... Rivaroxaban #Edoxaban #heparin
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Anticoagulation: • Initial heparin ... thrombin inhibitor (dabigatran ... (rivaroxaban, apixaban