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pharmacology anticoagulation management hematology diagnosis doac table cardiology dosing anticoagulant inr coumadin medications noac clinical coagulation dabigatran differential reversal rivaroxaban
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Warfarin and DOAC ... Rivaroxaban - Apixaban ... - Edoxaban Target ... #rivaroxaban #apixaban ... #edoxaban
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Reversal Agents - Warfarin ... (Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Anticoagulant Agents Warfarin ... Hepatic, 0% Renal Apixaban ... Hepatic, 80% Renal Edoxaban
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
: Rivaroxaban, Apixaban ... , Edoxaban • Vitamin ... K Antagonists: Warfarin
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Clotting Time Warfarin ... Rivaroxaban Apixaban ... , Edoxaban Argatroban
Warfarin to DOAC and DOAC to Warfarin Transitions Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... patients from warfarin ... Quick tip: apixaban ... Edoxaban is <2.5
Anticoagulant Sites of Absorption Apixaban - Primarily proximal small intestine; some gastric absorption Dabigatran - Lower stomach and
of Absorption Apixaban ... and duodenum Edoxaban ... gastric absorption Warfarin
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Bivalirudin, Dabigatran, Apixaban ... , Betrixaban, Edoxaban ... , Rivaroxaban, Warfarin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
anticoagulant #Warfarin ... thrombin #inhibitor #Apixaban ... #Rivaroxaban #Edoxaban
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban
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