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diagnosis differential causes hematology high management nephrology algorithm medications pathophysiology anemia deficiency druginduced product reactions treatment adverseeffects aldosterone angiotensin benefits
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... ischemia-induced RBC hemolysis ... ) • RBC Hemolysis ... Algorithm #causes #potassium
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... diet • Blood ... • Tumor lysis/hemolysis ... • Type 1 #Hyperkalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... Crush injury • Blood ... • Recent IV potassium ... cell lysis: - Hemolysis ... Blood transfusion
Massive Hemoptysis - Diagnosis and Management • Definitions: - Hemoptysis = bleeding from
Massive Hemoptysis ... Definitions: - Hemoptysis ... cords - Pseudo-hemoptysis ... cause death by asphyxia ... or blood loss
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... Crush injury • Blood ... • Recent IV potassium ... cell lysis: - Hemolysis ... Blood transfusion
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... • Peripheral blood ... bodies, DAT (-) → G6PD ... Immune mediated hemolysis ... Microangiopathic hemolytic
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... intoxication - Hyperkalemic ... Transfusion of aged blood ... - Hemolysis (
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Enzyme Defects: G6PD ... - Peripheral Blood ... Urobilinogen #Hemolysis
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... dietary intake • Blood ... MCW_Nephrology #HyperKalemia
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Benyzlpenicillin, blood ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
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