13 results
diagnosis differential causes high hematology algorithm nephrology management product reactions calculation classification comparison effects hemolytic index lactated lr normal ns
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... • Peripheral blood ... bodies, DAT (-) → G6PD ... → Sickle Cell anemia ... Immune mediated hemolysis
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... ischemia-induced RBC hemolysis ... ) • RBC Hemolysis ... Algorithm #causes #potassium
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... diet • Blood ... • Tumor lysis/hemolysis ... • Type 1 #Hyperkalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... Crush injury • Blood ... • Recent IV potassium ... cell lysis: - Hemolysis ... Blood transfusion
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... Crush injury • Blood ... • Recent IV potassium ... cell lysis: - Hemolysis ... Blood transfusion
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... > 3: • Acute blood ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... , G6PD deficiency
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Enzyme Defects: G6PD ... Defects: Sickle cell anemia ... - Peripheral Blood ... Urobilinogen #Hemolysis
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... intoxication - Hyperkalemic ... Transfusion of aged blood ... - Hemolysis (
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... Crush injury, Hemolysis ... • Pseudo hyperkalemia ... : Blood draw error ... Diagnosis #Causes #potassium
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
antibodies leading to hemolysis ... Hemolysis on labs ... , fever, minor hemolysis ... Hypocalcemia, Hyperkalemia ... potassium from
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