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diagnosis differential algorithm hypokalemia high low management chloride cushings diuresis diuretics endocrinology excretion gitelman hypercortisolism hyponatremia medications pathophysiology pharmacology renal
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... Alkalosis: Emesis ... #nephrology #low
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Diagnosis #Algorithm #causes ... #potassium #low ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Causes of Hyponatremia ... tubal acidosis and metabolic ... alkalosis, Ketonuria ... renal failure Hypervolemia ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... the indicated causes ... of sodium and potassium ... #Metabolic #Alkalosis ... urine #Algorithm #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... • Severe potassium ... after fasting #Metabolic ... #Diagnosis #Causes ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Tumor lysis syndrome ... infusions) - Metabolic ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Tumor lysis syndrome ... infusions) - Metabolic ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal ... (renal potassium ... Hypochloremic metabolic ... Supplement: • Potassium ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Heat stroke - Metabolic ... Monitor potassium ... Diagnosis #Management #causes ... #treatment #nephrology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Neuropsychological: lethargy ... Endocrine and metabolic ... Cataracts Labs: Hypokalemia ... alkalosis (Due
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