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diagnosis hematology differential rheumatology testing algorithm causes chronic disease erythematosus gap globulin hemolytic leukemia lupus lymphocytic oncology platelet protein proteingap
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... genotypes): SS, SC, SE ... membrane disorder ... Diagnosis #Algorithm #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Lymphocytosis on CBC ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... more time for the laboratory ... metabolic or endocrine disorders ... #laboratory #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... ) • Endocrine disorders ... with: • Minimal laboratory ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Connective tissue disorders ... (RA, Temporal arteritis ... autoimmune hepatitis, PBC ... anemia • Other
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