4 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... juvenile idiopathic arthritis ... leishmaniasis, brucellosis ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Complete blood count (CBC ... #laboratory #workup ... diagnosis #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... Chronic B-cell activation
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... (RA, Temporal arteritis ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia