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diagnosis hematology algorithm hemolytic classification cold disease folate folicacid gap globulin hodgkins homocysteine lymphoma macrocytic macrocytosis management mma oncology protein
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... Hyperbilirubinemia • Elevated ... Blood smear - RBC ... younger pts) Differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
(RBC = red blood ... reticulocyte count is elevated ... of the initial work-up ... Homocysteine #Algorithm #Workup ... #AAFP
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... #Differential # ... Diagnosis #Algorithm #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... schistocytes, nucleated RBCs ... immune hemolytic anemia ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... Inflammatory marker elevated ... Immunohistochemical studies (to differentiate
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Elevated Globulin ... Albumin > 4) Work-up ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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