10 results
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
(RBC = red blood ... the most likely cause ... recovery also causes ... of the initial work-up ... Homocysteine #Algorithm #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... changes), high MCV anemia ... disease), HBsAg/anti-HBc ... #Workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... are caused by prerenal ... CONSIDER INTRINSIC CAUSES ... microscopy for WBCs, RBCs ... KidneyInjury #simplified #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... schistocytes, nucleated RBCs ... immune hemolytic anemia ... from ischemia WBC ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... skin that are caused ... Workup: • Complete ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... classification #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Causes of Monoclonal ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia ... • Other causes
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
• No CRAB - no anemia ... • CBC + diff • ... #Plasmacytoma #Oncology ... #Diagnosis #Workup