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diagnosis hematology differential macrocytosis workup aafp cobalamin deficiency elevatedmcv folicacid homocysteine management mcv mma nutrition vitamin vitaminb12
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Framework by MCV Microcytic ... Infections Macrocytic ... Megaloblastic: Folate ... deficiency, B12
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... 95 (or 100) is macrocytic ... 14.5% suggests wide ... Workup #Hematology #Microcytic ... #Macrocytic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Drugs Oval Macrocytes ... Increased Requirement (e.g ... Liver Disease #Macrocytic ... #Causes #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... the most likely cause ... recovery also causes ... #Macrocytosis #Macrocytic
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... : • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... total body stores Evaluation
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