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diagnosis hematology differential macrocytosis aafp causes cobalamin deficiency elevatedmcv folate folicacid homocysteine management mcv mds mma myelodysplasia myelodysplastic nutrition oncology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... MatthewHoMD #Macrocytic ... #diagnosis #algorithm ... #hematology #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... 95 (or 100) is macrocytic ... (EPO), iron or B12 ... #Workup #Hematology ... #Microcytic #Macrocytic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Framework by MCV Microcytic ... Infections Macrocytic ... Folate deficiency, B12 ... Non-megaloblastic: Liver disease
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... • Drugs Oval Macrocytes ... • Pancreatic Disease ... • Liver Disease ... #Macrocytic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... of the initial work-up ... #Macrocytosis #Macrocytic ... #Workup #AAFP
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
: • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... to IBD, celiac disease ... Check for IF ab Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Workup: • Complete
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