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diagnosis hematology aafp cobalamin deficiency differential folate folicacid macrocytosis management mds microcytic mma myelodysplasia myelodysplastic nutrition oncology syndromes vitamin vitaminb12
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... of the initial work-up ... FolicAcid #MMA #Homocysteine ... #Algorithm #Workup
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... 95 (or 100) is macrocytic ... (EPO), iron or B12 ... #Workup #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
: • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... Elevated MMA and homocysteine ... Check for IF ab Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Nutritional: vitamin B12 ... factor (GCSF) treatments ... Workup: • Complete
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