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diagnosis differential hematology causes blurry cobalamin deficiency elevatedmcv evaluation falls geriatrics hemolytic macrocytosis management mds microcytic myelodysplasia myelodysplastic neurology nutrition
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... Hypothyroid • Liver Disease ... #diagnosis #algorithm ... #hematology #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 95 (or 100) is macrocytic ... (EPO), iron or B12 ... (BM) ablative disorders ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... • Drugs Oval Macrocytes ... • Small Bowel Disorder ... • Liver Disease ... #Macrocytic
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... chronic kidney disease ... - Vitamin B12 ... Probable bone marrow disorder ... #differential #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... vasculitis, malignant hypertension ... Consider RBC membrane disorder ... #workup #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
gastric acidity, medications ... dysfunction, and/or disorders ... : • Worsening macrocytic ... anemia, yellow ... to IBD, celiac disease
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Approach to Eye Disease ... Refractive Errors 12 ... immunosuppressive disorder ... • Systemic disorder ... retinopathy (sickle cell anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... common cytopenia: Macrocytic ... Myeloproliferative Disease ... Nutritional: vitamin B12
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
- Orthostatic hypotension ... embolism - Severe anemia ... exertional symptoms, hypotension ... e.g., diabetic, B12 ... Contributing Factors • Medications
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