14 results
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
the most likely cause ... recovery also causes ... of the initial work-up ... deficiency. ... #AAFP
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... Lactic Acidosis - Differential ... Causes of Lactate ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency
FAT RBC Mnemonic for Causes of Macrocytic Anemia
(MCV > 100)

F - Folate (Fetus) and B12 Deficiency
FAT RBC Mnemonic ... Folate (Fetus) and B12 ... Deficiency - Impairs ... released from marrow as ... #Anemia #Differential
Altered Mental Status - Differential Diagnosis
 • Neurologic: Stroke, Cerebral hypoxia, Cerebral hemorrhage, Seizure, Trauma, TBI,
Mental Status - Differential ... Diagnosis • Neurologic ... Hypercarbia, Vitamin deficiency ... Mental #Status #AMS ... Diagnosis #Causes
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... report dehydration as ... /other causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... to repair DNA, as ... , GATA2 deficiency ... , CTLA4 deficiency ... propylthiouracil) - β-lactam
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... dosing) L L-lactate ... ) D D-lactate ... Renal failure (uremia ... Diagnosis #Summary #Nephrology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Haptoglobin - Low as ... elevation Serum lactate ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... CPK aldolase, lactate