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diagnosis differential management cord hematology oncology spinal spinalcord acidosis algorithm alkaline alp aplastic arteritis behcet classification cobalamin disease disorders elevation
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... • Thiamine B1 ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... #symptoms #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 ... treatment can improve symptoms ... (chronic B1 deficiency ... Encephalopathy #B1 ... Diagnosis #Management #neurology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... , alcohol use, symptoms ... diagnosis #management #nutrition
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... • Improve the symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... treatments • Copper deficiency
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... Lower motor neuron symptoms ... Upper motor neuron symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic sx + signs ... systemic complaints- anemia ... GCA #Temporal #Signs
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... - Compartment syndrome ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... oral ulcers in 12 ... diagnosis #management #signs
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