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diagnosis management algorithm hematology oncology aafp alkaline aplastic arteritis cobalamin folate folicacid gca giantcell hepatology homocysteine hyophosphatasia ibd low macrocytic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... elevated, but anemia ... megaloblastic anemia ... Macrocytosis #Macrocytic #Anemia ... #VitaminB12 #Folate
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
despite clinical ... , Anemia • Prevalence ... Crohn's > UC Anemia ... restricted diet/deficiency ... /other causes •
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... deficiency. ... The classic clinical ... of pernicious anemia ... #NitrousOxide #VitaminB12
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Clinical Presentation ... : • Fever • Fatigue ... and petechiae Causes
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... subtle e.g. extreme fatigue ... systemic complaints- anemia ... identifies 85 to 95% of cases
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