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diagnosis management hematology nutrition oncology signs algorithm alkaline aplastic arteritis cobalamin differential gca giantcell hepatology hyophosphatasia ibd low mds myelodysplasia
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... • Thiamine B1 ... gestation • Vitamin B12 ... diagnosis #signs #symptoms
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... restricted diet/deficiency ... symptoms even if
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... slowing, neuropathy, fatigue ... to manifest its symptoms ... , alcohol use, symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... , GATA2 deficiency ... , CTLA4 deficiency ... • Improve the symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... subtle e.g. extreme fatigue ... systemic complaints- anemia ... Temporal #Signs #Symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... : • Fatigue • ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency
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