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diagnosis differential hematology management acidosis alkaline alp classification cobalamin elevation evaluation falls geriatrics hepatology hyophosphatasia lactate lactic mds myelodysplasia myelodysplastic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... and petechiae Causes ... #Anemia #oncology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... diagnosis #management #nutrition
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... ) - Waddling gait ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... diagnosis #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... LV failure - Low ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... e.g., diabetic, B12 ... deficiency) ... range of motion, gait ... Evaluation #Geriatrics #Neurology
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