10 results
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
despite clinical ... restricted diet/deficiency ... symptoms even if ... wnl B12 Patient ... /other causes
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... slowing, neuropathy, fatigue ... parasthesias, gait
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... and petechiae Causes ... • Improve the symptoms ... #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
reactivation of latent ... should be based on clinical ... status, and focal neurologic ... Demyelinating disease caused ... , limb ataxia, gait
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... exposure to or symptoms ... tabes dorsalis, gait ... similar to those of B12 ... deficiency.
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... : • Fatigue • ... Nutritional: vitamin B12 ... or folic acid deficiency ... diagnosis #hematology #oncology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Hyperreflexia develops later ... • Infectious causes ... • Nutritional Deficiency
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... subtle e.g. extreme fatigue ... systemic complaints- anemia ... Temporal #Signs #Symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS ... blindness, or gait ... • Parvovirus B19