14 results
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine ... (vitamin B1) deficiency ... ataxia (broad-based gait ... thiamine #deficiency ... #comparison #neurology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins: • Thiamine ... Wernicke-Korsakoff ... syndrome • Riboflavin ... gestation • Vitamin B12
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
(Thiamine) Deficiency ... dysfunction (e.g. gait ... syndrome (chronic ... B1 deficiency) ... #Thiamine #Deficiency
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... presentation of Thiamine ... deficiency, consequent ... #Syndrome #neurology
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Water-Soluble Vitamins: • Thiamine ... oculomotor dysfunction, gait ... ataxia), Korsakoff ... syndrome (amnesia ... • Vitamin B12
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... #oncology #hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... diagnosis #hematology #oncology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... Lower motor neuron symptoms ... Upper motor neuron symptoms