11 results
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... require urgent nephrology ... IMPROVEMENT If the urine ... creatinine (in 12 ... workup #diagnosis #nephrology
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Syndrome - UTI caused ... hemolysis (G6PD deficiency ... , sickle cell anemia ... Differential #Diagnosis #nephrology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology ... #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
excretion (e.g., urine ... of lactate as a clinical ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency ... differential #diagnosis #neurology
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
100 mOsm/kg = Urine ... chemotherapy, nausea ... • Cortisol deficiency ... Cancer #algorithm #nephrology ... #oncology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Check Vitamin B12 ... • Infectious causes ... • Nutritional Deficiency ... diagnosis #management #neurology
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Dialyzer is rigid case ... (Sustained low efficiency ... daily dialysis): ~12 ... Corrects uremia, ... RRT #managment #nephrology