61 results
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... diagnosis #signs #symptoms
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #neurology #nutrition
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... to repair DNA, as ... Treatment: ... • Improve the symptoms ... hematology #diagnosis #management
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... Encephalopathy Treatment ... #neurology #diagnosis
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... symptoms even if ... Algorithm #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... , alcohol use, symptoms ... Check for IF ab Treatment ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... /B12 deficiency ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
N2O can cause a syndrome ... deficiency. ... The classic clinical ... of pernicious anemia ... #Pathophysiology