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diagnosis differential management hematology oncology signs syndromes alkaline alp aplastic b1 behcet cobalamin cord disease encephalopathy erythematosus hepatology hyophosphatasia lesions
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... diagnosis #signs #symptoms ... #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
treatment can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency ... Diagnosis #Management #neurology ... #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... • Improve the symptoms ... #oncology #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... to manifest its symptoms ... , alcohol use, symptoms ... diagnosis #management #nutrition
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... insufficiency, blind loops syndromes ... malabsorption syndromes ... differential #diagnosis #hematology ... #nutrition
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... treatments • Copper deficiency
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... Lower motor neuron symptoms ... Upper motor neuron symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... oral ulcers in 12 ... #rheumatology #
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