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hematology oncology acidosis alkaline alp aplastic classification differential elevation hyophosphatasia lactate lactic low management mds myelodysplasia myelodysplastic phosphatase syndromes typea
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... Hyophosphatasia #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
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