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hematology management oncology acidosis acute alkaline alp aplastic causes classification cobalamin differential elevation hyophosphatasia kidneyinjury lactate lactic mds myelodysplasia myelodysplastic
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... : • Vit B12 - aka ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency ... #diagnosis #management
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
e.g AEIOU ) or anuria ... : Hypovolemia, Low ... creatinine (in 12 ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... may result from low ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... LV failure - Low ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
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