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diagnosis acidosis algorithm alkaline causes classification elevation fatigue hematology hepatology hyophosphatasia ibd lactic low management mds myelodysplasia myelodysplastic nutrition oncology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... • Thiamine B1 ... gestation • Vitamin B12 ... #differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... is critical for ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... Receptor (sTfR) to differentiate ... restricted diet/deficiency
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... CPK aldolase, lactate ... #Diagnosis #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential
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