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diagnosis causes hematology algorithm management acidosis alkaline classification disorders elevation fatigue hepatology hyophosphatasia ibd lactate lactic low macrocytic myelitis myelodysplasia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Deficiency • ... MDS+ • Hypothyroid ... #differential # ... algorithm #hematology #workup
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... • Thiamine B1 ... gestation • Vitamin B12 ... #differential #
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... is critical for ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... Receptor (sTfR) to differentiate ... restricted diet/deficiency
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... heavy metals), Critical ... : Acid maltase deficiency ... Weakness #Causes #differential ... #diagnosis #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... not required in all
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology ... #differential
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