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diagnosis algorithm management aafp alkaline cobalamin differential fatigue folate folicacid hematology hepatology homocysteine hyophosphatasia ibd low macrocytosis mds myelodysplasia myelodysplastic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... red blood cell; MMA ... serum level for all ... of the initial work-up ... deficiency.
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Beri-beri, Wernicke-Korsakoff ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... - Elevated MMA ... diagnosis #management #nutrition
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... (B12, MMA) for ... restricted diet/deficiency
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... is critical for ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Platelet Disorders • Nutritional ... : vitamin B12 or ... Workup: • Complete
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