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diagnosis algorithm differential hematology management aafp alkaline alp causes cobalamin elevatedmcv fatigue folate folicacid hepatology homocysteine hyophosphatasia ibd low mds
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Drugs Oval Macrocytes ... • Dietary Deficiency ... and Folate Deficiency ... Liver Disease #Macrocytic ... #Anemia #Macrocytosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... of the initial work-up ... deficiency is present ... deficiency. ... #Macrocytic #Anemia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... hypersegmented neutrophils, macrocytosis ... diagnosis #management #nutrition
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... , Anemia • Prevalence ... Crohn's > UC Anemia ... If persistent macrocytosis ... restricted diet/deficiency
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Platelet Disorders • Nutritional ... : vitamin B12 or ... Workup: • Complete
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... antibodies • Nutritional ... Deficiency: - ... Vitamin B12, E, ... diagnosis #management #neurology
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