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Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Encephalopathy vs Korsakoff ... Syndrome - Thiamine ... and retrograde amnesia ... #vitaminB1 #B1 # ... #comparison #neurology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Beri-beri, Wernicke-Korsakoff ... syndrome • Riboflavin ... signs #symptoms #nutrition
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
of Low Vitamin B12 ... Levels Low vitamin B12 ... and Sjögren's syndrome ... Food-bound cobalamin ... antagonists #VitaminB12
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
development of Korsakoff ... syndrome (chronic ... B1 deficiency) ... Diagnosis #Management #neurology ... #nutrition
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #Syndrome #neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency ... diagnosis #management #nutrition
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
N2O can cause a syndrome ... deficiency. ... The classic clinical ... of pernicious anemia ... #NitrousOxide #VitaminB12
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... insufficiency, blind loops syndromes ... malabsorption syndromes ... #VitaminB12 #deficiency ... diagnosis #hematology #nutrition
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... Workup: • Complete