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diagnosis hematology korsakoff pathophysiology syndromes b1 causes classification encephalopathy management wernickes acidosis algorithm bariatric beriberi bypass cobalamin comparison cord deficiencies
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins: • Thiamine ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... #differential #
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
(Thiamine) Deficiency ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #Thiamine #Deficiency ... Diagnosis #Management #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... (vitamin B1) deficiency ... #vitaminB1 #B1 # ... thiamine #deficiency ... diagnosis #comparison #neurology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
of Low Vitamin B12 ... Levels Low vitamin B12 ... and Sjögren's syndrome ... antagonists #VitaminB12 ... #cobalamin #differential
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine ... deficiency, consequent ... #neurology #diagnosis
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Water-Soluble Vitamins: • Thiamine ... ataxia), Korsakoff syndrome ... • Vitamin B12 ... Bypass #vitamin #nutrition ... #table #differential
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
Thiamine Deficiency ... - Differential ... Framework and Clinical ... #Differential # ... #beriberi #nutrition
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... may cause severe clinical ... (thiamine) Late ... arrhythmias • Thiamine ... #Nutrition #Differential
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... malabsorption syndromes ... #VitaminB12 #deficiency ... #differential # ... diagnosis #hematology #nutrition
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