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diagnosis differential management hematology oncology algorithm nutrition acidosis alkaline alp aplastic causes cobalamin dementia dysfunction elevation erythematosus fatigue folate folicacid
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... elevated, but anemia ... megaloblastic anemia ... Macrocytosis #Macrocytic #Anemia ... #AAFP
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... E - Haemolytic anaemia ... paraesthesiae • Folate - Anaemia ... gestation • Vitamin B12 ... - Anaemia, neurological
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... intrinsic factor, IF) Clinical ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... Clinical Presentation ... • Improve the symptoms
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... , Anemia • Prevalence ... Crohn's > UC Anemia ... restricted diet/deficiency ... symptoms even if
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical ... Whipple, vitamin deficiency ... - Progressive amnesia ... Aphaso-apraxo-agnosia ... Differential #Subtypes #Classification
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... dyserythropoietic anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms ... Hodgkin Lymphoma Workup
Anosmia Causes - Principal Etiologies of Olfactory Dysfunction For olfactory disorders (and for most taste problems), the
Anosmia Causes - ... these conditions.12 ... with memory or neurologic ... #Differential #Anosmia ... #Dysfunction #AAFP
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